Correlated Motions and Dynamics in Different Domains of EGFR With L858R and T790M Mutations
Molecular dynamics of the EGFR L858R and T790M mutations, using cross-correlation and community network analysis.
IEEE Conference Proceedings, 2020.
Note
Simulates the two mutations behind EGFR inhibitor resistance and identifies how correlated motion between receptor domains changes when they are present.
Reference
Correlated Motions and Dynamics in Different Domains of EGFR With L858R and T790M Mutations IEEE Conference Proceedings, 2020. https://ieeexplore.ieee.org/document/9095428
The publisher record holds the author list.
Details
- TypeConference paper
- AreasDrug resistance in lung cancer